辣椒碱 CAS#:404-86-4_上海皓元生物医药科技有限公司

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辣椒碱

CAS号	404-86-4
规格	50mg100mg	纯度	98%
货号	HY-10448	货期	3天
品牌	Medchemexpress	库存	需咨询
规格	50mg100mg
纯度	98%
货号	HY-10448
货期	3天
品牌	Medchemexpress
库存	---
注意：请务必与卖家联系核实单价库存，以确保您的资金安全及交易顺利。
参考价：￥560.00 元/50mg

立即询盘

货号	品牌	纯度	规格	参考价	货期
HY-10448	Medchemexpress	98%	50mg100mg	￥560.00元/50mg	3天

产品详情

详细信息(中文)：
Capsaicin为辣椒的活性成分，能与辣椒素受体1（VR1）结合，能促使前列腺癌细胞和肺癌细胞的凋亡。

详细信息(英文)：
产品描述：CapsaicinCapsaicin, the active component of chili peppers, is a member of the vanilloid family, binds to a receptor called the vanilloid receptor subtype 1 (VR1). Capsaicin is able to kill prostate cancer and lung cancer cells by causing them to undergo apoptosis._x000D_ IC50 Value: 150 uM (MTT assay in FaDu cells) [1]_x000D_ in vitro: Treatment of A172 cells withcapsaicin inhibited cell growth and induced apoptosis through down-regulation of Bcl-2 and activation of caspase-3. Interestingly, synergistic induction of morphological alternation was observed when A172 cells were treated with capsaicin [2]. After the addition of capsaicin, the levels of reactive oxygen species were reduced slightly in the earlier stage of treatment. Interestingly, an elevation of intracellular calcium ion concentration was detected in the MCF-7 cells [3]._x000D_ in vivo: Intraperitoneal administration of CAP (10mg/kg body weight) to Swiss albino mice suppressed the development of lung carcinoma by amending the protein expressions of 公司介绍：MedChemExpress(MCE)专注于各种抑制剂、激动剂、API及化合物库，总部位于美国新泽西，分别在瑞典和上海设有欧洲区子公司和亚洲区总代理，营销网点遍及全球20多个国家地区。MCE经过多年努力已成为全球生物活性小分子领域的一流供应商，产品涵盖癌症、神经科学、抗感染、表观遗传学等20个热门研究领域，PI3K、MAPK等近千个细分靶点，超过4000个活性小分子化合物现货，以及GPCR、API、离子通道等超过20种不同类型的化合物库，同时提供从毫克到千克的专业定制合成服务。 MCE 对每批产品都进行严格的LCMS和NMR检验，其产品已被全球近万名客户广泛使用并发表大量文章、专利； MCE 定期增加各领域热门抑制剂、激动剂，不断扩增已有化合物库，以满足最新的科研需求；数千种产品在上海有充足备货，24-48小时内送达客户；大量产品提供免费试用装；已为全球多个知名企业、院校构建各种定制型化合物库。产品链接：www.medchemexpress.cn/capsaicin.html